Prostaglandins and rat glomerular mesangial cell proliferation

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Thromboxane A2, prostaglandins, and mesangial cell proliferation.

Much work has recently focused upon the cellular involvement of the mesangium in glomerular inflammation and fibrosclerosis. A host of mediators of inflammation have been identified and their actions studied in mesangial cell cultures [1]. The recent identification of functional receptors for prostaglandins (PG) and thromboxane A2 (TxA2) in cultured glomerular mesangial cells [2, 3] has prompte...

متن کامل

Cell Proliferation in Glomerular Mesangial and Vascular Smooth Muscle Cells

Vascular Smooth Muscle Cells GATA-6: The Proliferation Stops Here : Cell Proliferation in Glomerular Mesangial and Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2000 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.87.8.638 2000;87:638-640 Circ Res. ...

متن کامل

GATA-6: the proliferation stops here: cell proliferation in glomerular mesangial and vascular smooth muscle cells.

GATA-6 belongs to a family of zinc finger transcription factors that have been implicated in various developmental processes, including cell differentiation and proliferation. In this issue of Circulation Research, Nagata et al1 report that overexpression of GATA-6 in glomerular mesangial cells (GMCs) results in decreased cell proliferation and posttranscriptional upregulation of p21, a cyclin-...

متن کامل

The activated mesangial cell: a glomerular "myofibroblast"?

The glomerular mesangial cell may have several important beneficial functions in the normal glomerulus. These include the production of growth factors to allow normal cell turnover, the provision of structural support for the capillaries via the production of mesangial matrix, and the modulation of glomerular hemodynamics via their contractile properties. However, in various types of glomerular...

متن کامل

Simvastatin suppresses glomerular cell proliferation and macrophage infiltration in rats with mesangial proliferative nephritis.

Inhibition of 3-hydro-3-methylglutaryl coenzyme A reductase inhibits the production of mevalonate and has been shown to suppress proliferation in many cell types. Therefore, 3-hydro-3-methylglutaryl coenzyme A reductase inhibitors may have a beneficial effect in glomerular disease, because glomerular cell proliferation is a central feature in the active glomerular injury. This study examines th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Kidney International

سال: 1990

ISSN: 0085-2538

DOI: 10.1038/ki.1990.109